Women taking steroids are susceptible to the same risks for heart and liver health as men. However, one of the primary concerns among our patients is preventing masculinization. Women have limited steroid options that won’t lead to irregular periods, clitoral hypertrophy, a deeper voice, scalp hair loss, torso hair growth, or a wider jaw.
Nevertheless, we have found that Anavar and Anadrol (at appropriate doses) are effective steroids that prevent virilization while supporting muscle growth and fat loss simultaneously. Both are utilized in medicine to treat cachexia. Are steroids safe for women? The medical literature indicates that they are safe when taken short-term in therapeutic doses under medical supervision.
The role of steroids in women’s health
We have already answered the question “Are steroids harmful to women’s health?” but it is time to explaining that steroids play an important role in different methods of women’s treatment. They help to treat afflictions such as hormonal imbalances, some cancers and autoimmune diseases. Controlled use of steroids under medical supervision may have a significant impact on women’s health.
Testosterone in women’s body system has several important functions:
Synthesis of Estradiol: Testosterone is converted to estradiol by the aromatase enzyme. High activity of aromatase is found primarily in the ovaries, chest, liver and adipose tissue.
- Muscle tissue development: Testosterone stimulates muscle tissue development through various mechanisms. It affects pluripotent stem cells, which results in the formation of satellite cells and myocytes and inhibits the formation of adipocytes.
- Increased production of proteins: Testosterone increases biosynthesis of proteins, which is important for the body’s metabolic processes.
- Support for erythrocyte and bone formation: Testosterone affects the process of formation of red blood cells and has a beneficial impact on bone density.
- Antiproliferative effect: Testosterone may have antiproliferative effects by binding to androgen receptors in the chest, which suggest its potential role in preventing breast cancer.
During premenopause time about half of testosterone is released through the conversion of androstendione and dehydroepiandrosterone (DHEA) in peripheral tissues, while ovaries and adrenal cortex contribute to the remaining production.
During menopause, when ovarian hormone production gradually decreased, women produce less testosterone and estradiol, which can lead to various menopausal symptoms, such as reduced bone density and decreased sexual desire.
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Treatment of testosterone deficiency in women
Treatment of testosterone deficiency in women is a topic of still discussion in the medical sphere. The global consensus on the use of testosterone in women recommends testosterone therapy in women after ovarian resection or in postmenopausal time with pathologically reduced sexual interests (Hypoactive Sexual Desire Disorder – HSDD). In premenopausal women physiological testosterone levels should be achieved. Women can receive estrogen therapy at the same time.
Are steroids harmful to women’s health? Possible side effects
Steroids are safe for women when they are taken short-term in therapeutic doses under medical supervision but even than sometimes they may cause side effects. For example, those are possible side effect of taking testosterone steroids by women:
- Virilization (masculinization) in women
All anabolic steroids cause virilization in women due to their androgenic effects, which manifests as changes in voice (irreversible), hair pattern, menstrual cycle disorders and clitoral hypertrophy (irreversible).
- Damage of cardiovascular system
During the use of anabolic steroids plasma concentrations of high-density lipoprotein (HDL = High Density Lipoprotein) decrease, while low-density lipoprotein (LDL = Low Density Lipoprotein) increases. This causes an increase in the ratio of LDL to HDL, which is seen as a risk factor for atherosclerosis and even heart attack.
- Damage of liver
Long-term use of anabolic steroids can cause irreversible liver damage. It’s believed that 17-methylated steroids, such as methyltestosterone or stanozolol, have more toxic effects on liver cells than unmethylated steroids, such as testosterone. In this connection, for therapeutic purposes testosterone compounds are now preferred instead of 17-methylated steroids.
Use of testosterone by women – recommendations
Are steroids safe for women?
Yes, but it is recommended to carefully medicate testosterone in women, especially to avoid doses that may lead to exceeding the physiological values and to monitor side effects. The preferred method of testosterone taking is transdermal, and use should be carefully monitored for improvement in the patient’s condition. The possibility of pregnancy should also be ruled out because testosterone may have negative effects on the developing fetus.